Your country and language has been automatically selected.

Back

p-Aminobenzamidine Dihydrochloride BioChemica

Assay (titr.): 98.0 - 101.0 %
Code
A2126
CAS
2498-50-2
Molecular Formula
C7H9N3 · 2HCl
Molar mass
208.09 g/mol
Physical Description:
Solid
Product Code:
A2126
Product Name:
p-Aminobenzamidine Dihydrochloride BioChemica
Specifications:
Assay (titr.): 98.0 - 101.0 %
Loss on drying (105°C): max. 1.0 %
Comment:
p-Aminobenzamidine is, like benzamidine, a competitive inhibitor of the serine proteases trypsin (1), plasmin and thrombin (2), but it is more active than benzamidine. The active concentration ranges from 1 mM (3, 4) to 2 mM (5). For the preparation of plant cell extracts, a working concentration of 1 mM is recommended (100X stock solution 0.1 M in water; ref. 4).
Bibliography:
(1)Mares-Guia, M. & Shaw, E. (1965) J. Biol. Chem. 240, 1579-1585Studies on the active center of Trypsin\: The binding of Amidines and Guanidines as models of the substrate side chain. (2)Markwardt, F. et al. (1968) Eur. J. Biochem. 6, 502-506Comparative studies on the inhibition of Trypsin, Plasmin and Thrombin by derivatives of Benzylamine and Benzamidine. (3)Hanatani, M. et al. (1984) J. Biochem. 95, 1349-1353Solubilization and reconstitution of membrane proteins of E. coli using Alkanoyl-N-methylglucamides. (4)Gegenheimer, P. (1990) Methods Enzymol. 182, 174-193Preparation of extracts from plants. (5)Hager-Braun, C. et al. (1995) Biochemistry 34, 9617-9624Stable photobleaching of P480 in Chlorobium reaction center preparations\: Presence of the 42-kDa Bacteriochlorophyll a protein and a 17-kDa polypeptide.
Hazard pictograms
  • GHS07 Hazard
WGK:
1
Storage:
2-8°C
Signal Word:
Attention
GHS Symbols:
GHS07
H Phrases:
H315
H319
H335
P Phrases:
P261
P305+P351+P338
EINECS:
219-692-2
CS:
29252900
Download TDS file for complete specifications